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Venlafaxine (Effexor XR) versus an SSRI

Is venlafaxine more efficacious for the treatment of major depressive disorder than the SSRIs? This question has been addressed by several meta-analyses that combined the data from the numerous individual studies that directly compared venlafaxine to an SSRI. One metaanalysis (Papakostas et al., 2007) combined 93 clinical trials (n = 17,036). It found that response…

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