Which causes more weight gain—venlafaxine or duloxetine?

  Question from a Member: I have a patient who is on duloxetine 90 mg/day and feels it is the reason for her weight gain. She wants to switch to venlafaxine, another SNRI [serotonin-norepinephrine reuptake inhibitor]. Will this help? Direct (head-to-head) comparison of venlafaxine and duloxetine By “direct” and “head-to-head” comparison we mean that it…