What is 7-aminoclonazepam and why is it tested for in the urine?

What is it? 7-aminoclonazepam is an active metabolite of clonazepam. Clonazepam is extensively metabolized in the liver, mainly by CYP3A4, to its main metabolite 7-aminoclonazepam (Storhoug et al., 2012). Why is it important to us? Only 0.5% of a dose of clonazepam is excreted unchanged in the urine (Negrusz et al., 2003). So, if a person…