Nortriptyline (US brand name Pamelor® and generic) is a tricyclic antidepressant. Here is basic information about this medication.
Major depressive disorder
Recommended adult dosage: 25 mg orally, 3-4 times per day, or 100 mg once daily
Maximum: 150 mg/day
Elderly: 30–50 mg/day in divided doses or once daily
a) For doses above 100 mg/day, plasma levels of nortriptyline need to be monitored and maintained between 50–150 ng/mL
b) At least 14 days should elapse between discontinuation of an MAOI and initiation of therapy with nortriptyline. Conversely, at least 14 days should be allowed after stopping nortriptyline before starting an MAOI.
Dosage forms and strengths
Capsule (Pamelor® and generic): 10 mg, 25 mg, 50 mg, and 75 mg
Oral Solution (generic): 10 mg base/5 mL
Important! Please refer to the full Prescribing Information (see link below) before prescribing this medication.
Which tricyclic antidepressants (TCAs) are the most effective ones for major depressive disorder (MDD)?
Copyright 2016, Rajnish Mago, MD. All rights reserved. May not be reproduced in any form without express written permission.
Disclaimer: The content on this website is provided as general education for medical professionals. It is not intended or recommended for patients or other laypersons, or as a substitute for medical advice, diagnosis, or treatment. Patients must always consult a qualified health care professional regarding their diagnosis and treatment. Healthcare professionals should always check this website for the most recently updated information.