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Lamotrigine blood levels are correlated with the dose of lamotrigine in persons taking lamotrigine alone as well in those taking another antiepileptic medication(s), including divalproex (Hirsch et al., 2004).
References
Clark CT, Klein AM, Perel JM, Helsel J, Wisner KL. Lamotrigine dosing for pregnant patients with bipolar disorder. Am J Psychiatry. 2013 Nov;170(11):1240-7. PubMed PMID: 24185239; PubMed Central PMCID: PMC4154145.
Devulder J. The relevance of monitoring lamotrigine serum concentrations in chronic pain patients. Acta Neurol Belg. 2006 Mar;106(1):15-8. PubMed PMID: 16776431.
Hirsch LJ, Weintraub D, Du Y, Buchsbaum R, Spencer HT, Hager M, Straka T, Bazil CW, Adams DJ, Resor SR Jr, Morrell MJ. Correlating lamotrigine serum concentrations with tolerability in patients with epilepsy. Neurology. 2004 Sep 28;63(6):1022-6. Review. PubMed PMID: 15452293.